BDBM50061255 1-(4-Fluoro-phenyl)-4-(3-phenyl-8-aza-bicyclo[3.2.1]oct-8-yl)-butan-1-one::1-(4-fluorophenyl)-4-(3-phenyl-8-aza-bicyclo[3.2.1]octan-8-yl)butan-1-one::CHEMBL340816::CHEMBL553417

SMILES Fc1ccc(cc1)C(=O)CCCN1C2CCC1CC(C2)c1ccccc1

InChI Key InChIKey=LECUUDCCVOYUHG-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50061255   

TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061255(CHEMBL340816 | CHEMBL553417 | 1-(4-Fluoro-phenyl)-...)
Affinity DataKi:  34.1nMAssay Description:Sigma-1 binding assay was done in guinea pig membranes by labeling the binding site with [3H](+)-pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061255(CHEMBL340816 | CHEMBL553417 | 1-(4-Fluoro-phenyl)-...)
Affinity DataKi:  88.5nMAssay Description:Binding affinity for serotonin transporter was determined in rat cortical membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(CHEMBL340816 | CHEMBL553417 | 1-(4-Fluoro-phenyl)-...)
Affinity DataKi:  106nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(CHEMBL340816 | CHEMBL553417 | 1-(4-Fluoro-phenyl)-...)
Affinity DataKi:  124nMAssay Description:Binding affinity for dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(CHEMBL340816 | CHEMBL553417 | 1-(4-Fluoro-phenyl)-...)
Affinity DataKi:  124nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061255(CHEMBL340816 | CHEMBL553417 | 1-(4-Fluoro-phenyl)-...)
Affinity DataKi:  129nMAssay Description:Binding affinity for dopamine transporter was determined in rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(CHEMBL340816 | CHEMBL553417 | 1-(4-Fluoro-phenyl)-...)
Affinity DataKi:  177nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(CHEMBL340816 | CHEMBL553417 | 1-(4-Fluoro-phenyl)-...)
Affinity DataKi:  177nMAssay Description:Binding affinity for dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(CHEMBL340816 | CHEMBL553417 | 1-(4-Fluoro-phenyl)-...)
Affinity DataKi:  414nMAssay Description:Binding affinity to human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50061255(CHEMBL340816 | CHEMBL553417 | 1-(4-Fluoro-phenyl)-...)
Affinity DataKi:  594nMAssay Description:Binding to vesicular acetylcholine transporter of torpedo synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(CHEMBL340816 | CHEMBL553417 | 1-(4-Fluoro-phenyl)-...)
Affinity DataKi:  974nMAssay Description:Binding affinity to human cloned histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50061255(CHEMBL340816 | CHEMBL553417 | 1-(4-Fluoro-phenyl)-...)
Affinity DataKi:  1.07E+3nMAssay Description:Binding affinity to human cloned 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed