BDBM500613 4-(1-methyl- 1H-pyrrolo[2,3- b]pyridin-4- yl)-7-((5-(4- methylpiperidin- 4-yl)pyridin-2- yl)amino)isoin- dolin-1-one::US11021481, Compound I-272::US11078201, Compound I-272::US11548890, Compound I-272

SMILES Cn1ccc2c(ccnc12)-c1ccc(Nc2ccc(cn2)C2(C)CCNCC2)c2C(=O)NCc12

InChI Key InChIKey=CMUKMWLVLGZSPT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500613   

LigandPNGBDBM500613(US11021481, Compound I-272 | 4-(1-methyl- 1H-pyrro...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

LigandPNGBDBM500613(US11021481, Compound I-272 | 4-(1-methyl- 1H-pyrro...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM500613(US11021481, Compound I-272 | 4-(1-methyl- 1H-pyrro...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM500613(US11021481, Compound I-272 | 4-(1-methyl- 1H-pyrro...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500613(US11021481, Compound I-272 | 4-(1-methyl- 1H-pyrro...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent