BDBM50061681 (R)-2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chroman-7-ol; oxalic acid::CHEMBL135044

SMILES Oc1ccc2CC[C@H](CN3CCc4ccccc4C3)Oc2c1

InChI Key InChIKey=IWUPLAFLTUWLMF-GOSISDBHSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50061681   

TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061681((R)-2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chro...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity at human Dopamine receptor D3 (hD3) using [3H]spiperone radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061681((R)-2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chro...)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061681((R)-2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chro...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity at human Dopamine receptor D2 (hD2) using [3H]spiperone radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061681((R)-2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chro...)
Affinity DataKi:  3.80nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the antagonist [3H]spiperone + GTP to label the low affinity stat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061681((R)-2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chro...)
Affinity DataKi:  34nMAssay Description:In vitro binding affinity to rat hippocampal 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061681((R)-2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chro...)
Affinity DataKi:  529nMAssay Description:Binding affinity at human Dopamine receptor D4 (hD4) using [3H]spiperone radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed