BDBM500617 4-(1-methyl- 1H-pyrrolo[2,3- b]pyridin-4- yl)-7-((5- morpholino- pyridin-2- yl)amino)-2,3- dihydro-1H- pyrrolo[3,4- c]pyridin-1-one::US11021481, Compound I-276::US11078201, Compound I-276::US11548890, Compound I-276

SMILES Cn1ccc2c(ccnc12)-c1ncc(Nc2ccc(cn2)N2CCOCC2)c2C(=O)NCc12

InChI Key InChIKey=DTLNBTLCQQPKRD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500617   

LigandPNGBDBM500617(US11021481, Compound I-276 | 4-(1-methyl- 1H-pyrro...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500617(US11021481, Compound I-276 | 4-(1-methyl- 1H-pyrro...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

LigandPNGBDBM500617(US11021481, Compound I-276 | 4-(1-methyl- 1H-pyrro...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM500617(US11021481, Compound I-276 | 4-(1-methyl- 1H-pyrro...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500617(US11021481, Compound I-276 | 4-(1-methyl- 1H-pyrro...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent