BDBM50062350 (R)-N*1*-((R)-2-Benzo[b]thiophen-3-yl-1-methylcarbamoyl-ethyl)-N*4*-hydroxy-2-isobutyl-succinamide::CHEMBL306912

SMILES CNC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO

InChI Key InChIKey=CBYPWAIEESKRSM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062350   

Target72 kDa type IV collagenase(Human)
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062350((R)-N*1*-((R)-2-Benzo[b]thiophen-3-yl-1-methylcarb...)
Affinity DataKi:  0.440nMAssay Description:Binding affinity towards 72 kDa gelatinase (Matrix metalloprotease-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062350((R)-N*1*-((R)-2-Benzo[b]thiophen-3-yl-1-methylcarb...)
Affinity DataKi:  0.450nMAssay Description:The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloprotease-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062350((R)-N*1*-((R)-2-Benzo[b]thiophen-3-yl-1-methylcarb...)
Affinity DataKi:  0.830nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed