BDBM50062790 ((S)-4-Carboxymethyl-1-{2-[(4-guanidinomethyl-cyclohexanecarbonyl)-amino]-acetyl}-3-oxo-piperazin-2-yl)-acetic acid::CHEMBL358154

SMILES N=C(N)NCC1CCC(C(=O)NCC(=O)N2CCN(CC(=O)O)C(=O)[C@@H]2CC(=O)O)CC1

InChI Key InChIKey=KHKDDKWZUSWRPL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062790   

TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062790BDBM50062790(((S)-4-Carboxymethyl-1-{2-[(4-guanidinomethyl-cycl...)
Affinity DataIC50: 20nMAssay Description:Ability to inhibit binding of biotin-labeled human fibrinogen to immobilized fibrinogen receptor purified from human erythroleukemia (HEL) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062790BDBM50062790(((S)-4-Carboxymethyl-1-{2-[(4-guanidinomethyl-cycl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of human platelets by 50% in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062790BDBM50062790(((S)-4-Carboxymethyl-1-{2-[(4-guanidinomethyl-cycl...)
Affinity DataIC50: 4.20E+3nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of guinea pig platelets by 50% in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed