BDBM50062803 3-((S)-1-{2-[4-(2-Amino-ethyl)-benzoylamino]-acetyl}-4-carboxymethyl-3-oxo-piperazin-2-yl)-propionic acid methyl ester::CHEMBL146979

SMILES COC(=O)CC[C@@H]1N(CCN(CC(O)=O)C1=O)C(=O)CNC(=O)c1ccc(CCN)cc1

InChI Key InChIKey=SHWNHVGERLWSSM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062803   

TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062803(3-((S)-1-{2-[4-(2-Amino-ethyl)-benzoylamino]-acety...)
Affinity DataIC50: 0.890nMAssay Description:Ability to inhibit binding of biotin-labeled human fibrinogen to immobilized fibrinogen receptor purified from human erythroleukemia (HEL) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062803(3-((S)-1-{2-[4-(2-Amino-ethyl)-benzoylamino]-acety...)
Affinity DataIC50: 110nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of guinea pig platelets by 50% in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062803(3-((S)-1-{2-[4-(2-Amino-ethyl)-benzoylamino]-acety...)
Affinity DataIC50: 120nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of human platelets by 50% in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed