BDBM50062808 CHEMBL147921::{(S)-4-Carboxymethyl-1-[2-(4-guanidinomethyl-benzoylamino)-acetyl]-3-oxo-piperazin-2-yl}-acetic acid

SMILES NC(=N)NCc1ccc(cc1)C(=O)NCC(=O)N1CCN(CC(O)=O)C(=O)[C@@H]1CC(O)=O

InChI Key InChIKey=MVSMMWWPHRKZSJ-ZDUSSCGKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062808   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062808(CHEMBL147921 | {(S)-4-Carboxymethyl-1-[2-(4-guanid...)
Affinity DataIC50:  18nMAssay Description:Ability to inhibit binding of biotin-labeled human fibrinogen to immobilized fibrinogen receptor purified from human erythroleukemia(HEL) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062808(CHEMBL147921 | {(S)-4-Carboxymethyl-1-[2-(4-guanid...)
Affinity DataIC50:  2.60E+3nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of guinea pig platelets by 50% in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062808(CHEMBL147921 | {(S)-4-Carboxymethyl-1-[2-(4-guanid...)
Affinity DataIC50:  560nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of human platelets by 50% in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed