BDBM500632 7-((5-(4-hydroxy- piperidin-1- yl)pyridin-2- yl)amino)-5- methyl-4-(1- methyl-1H- indol-4-yl) isoindolin- 1-one::US11021481, Compound I-292::US11078201, Compound I-292::US11548890, Compound I-292

SMILES Cc1cc(Nc2ccc(cn2)N2CCC(O)CC2)c2C(=O)NCc2c1-c1cccc2n(C)ccc12

InChI Key InChIKey=VTKGAQDPJWTBOE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500632   

LigandPNGBDBM500632(US11021481, Compound I-292 | 7-((5-(4-hydroxy- pip...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500632(US11021481, Compound I-292 | 7-((5-(4-hydroxy- pip...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

LigandPNGBDBM500632(US11021481, Compound I-292 | 7-((5-(4-hydroxy- pip...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM500632(US11021481, Compound I-292 | 7-((5-(4-hydroxy- pip...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM500632(US11021481, Compound I-292 | 7-((5-(4-hydroxy- pip...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent