BDBM50063391 1-[4-((S)-8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-(1-oxy-pyridin-3-yl)-ethanone::CHEMBL368450

SMILES [O-][n+]1cccc(CC(=O)N2CCN(CC2)[C@H]2c3ccc(Cl)cc3CCc3cccnc23)c1

InChI Key InChIKey=FWNUTUFWZCIFLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50063391   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063391(1-[4-((S)-8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclo...)
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro inhibition of farnesyltransferase farnesylation of the H-ras oncogeneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed