BDBM50063497 CHEMBL3398485

SMILES Cl.CCCCOc1nc(N)c2[nH]c(=O)n(CCC3CCNCC3)c2n1

InChI Key InChIKey=IKNBSENDDSMXOG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50063497   

TargetToll-like receptor 7(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50063497(CHEMBL3398485)
Affinity DataEC50:  150nMAssay Description:Activation of human TLR7 expressed in HEK293 cells after 24 hrs by NFkappaB-mediated SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50063497(CHEMBL3398485)
Affinity DataEC50:  2.31E+5nMAssay Description:Activation of human TLR8 expressed in HEK293 cells after 24 hrs by NFkappaB-mediated SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed