BDBM50064048 7-Benzyl-5,6,7,8-tetrahydro-pyrido[4',3':4,5]furo[2,3-d]pyrimidine-2,4-diamine::CHEMBL30403

SMILES Nc1nc(N)c2c3CCN(Cc4ccccc4)Cc3oc2n1

InChI Key InChIKey=LBCNVSANQLBTPU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50064048   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50064048(7-Benzyl-5,6,7,8-tetrahydro-pyrido[4',3':4,5]furo[...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50064048(7-Benzyl-5,6,7,8-tetrahydro-pyrido[4',3':4,5]furo[...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50064048(7-Benzyl-5,6,7,8-tetrahydro-pyrido[4',3':4,5]furo[...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory concentration was evaluated against CCRF-CEM Dihydrofolate reductase enzyme in Mycobacterium avium.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50064048(7-Benzyl-5,6,7,8-tetrahydro-pyrido[4',3':4,5]furo[...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed