BDBM50064091 (2S,5S)-9-Decyl-5-hydroxymethyl-2-isopropyl-1-methyl-1,4,5,6-tetrahydro-2H-benzo[e][1,4]diazocin-3-one::CHEMBL34971

SMILES CCCCCCCCCCc1ccc2C[C@@H](CO)NC(=O)[C@H](C(C)C)N(C)c2c1

InChI Key InChIKey=NAFNDRDUGFOXIC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50064091   

TargetProtein kinase C delta type(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50064091((2S,5S)-9-Decyl-5-hydroxymethyl-2-isopropyl-1-meth...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-PDBu from human recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50064091((2S,5S)-9-Decyl-5-hydroxymethyl-2-isopropyl-1-meth...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]PDBu from recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50064091((2S,5S)-9-Decyl-5-hydroxymethyl-2-isopropyl-1-meth...)
Affinity DataEC50:  25nMAssay Description:Activation of PKC in human ACH-2 cells infected with latent HIV-1 assessed as reversal of HIV-1 latency by measuring increase in p24 antigen level in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50064091((2S,5S)-9-Decyl-5-hydroxymethyl-2-isopropyl-1-meth...)
Affinity DataEC50:  34nMAssay Description:Activation of PKC in human U1 cells infected with latent HIV-1 assessed as reversal of HIV-1 latency by measuring increase in p24 antigen level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50064091((2S,5S)-9-Decyl-5-hydroxymethyl-2-isopropyl-1-meth...)
Affinity DataEC50:  6.30E+3nMAssay Description:Activation of PKC in human J-Lat 6.3 cells infected with latent HIV-1 assessed as reversal of HIV-1 latency by measuring increase of GFP-positive cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50064091((2S,5S)-9-Decyl-5-hydroxymethyl-2-isopropyl-1-meth...)
Affinity DataEC50:  1.06E+4nMAssay Description:Activation of PKC in human J-Lat 10.6 cells infected with latent HIV-1 assessed as reversal of HIV-1 latency by measuring increase of GFP-positive ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed