BDBM50064095 (7S,10S)-10-Hydroxymethyl-7-isopropyl-1,1,4,4,6-pentamethyl-2,3,4,6,7,9,10,11-octahydro-1H-6,9-diaza-cycloocta[b]naphthalen-8-one::CHEMBL35696

SMILES CC(C)[C@@H]1N(C)c2cc3c(cc2C[C@@H](CO)NC1=O)C(C)(C)CCC3(C)C

InChI Key InChIKey=TXTPQHMKEMQYBG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50064095   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50064095((7S,10S)-10-Hydroxymethyl-7-isopropyl-1,1,4,4,6-pe...)
Affinity DataEC50:  2.91E+3nMAssay Description:Activation of PKC in human ACH-2 cells infected with latent HIV-1 assessed as reversal of HIV-1 latency by measuring increase in p24 antigen level in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein kinase C delta type(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50064095((7S,10S)-10-Hydroxymethyl-7-isopropyl-1,1,4,4,6-pe...)
Affinity DataKi:  5.10E+3nMAssay Description:Displacement of [3H]PDBu from recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50064095((7S,10S)-10-Hydroxymethyl-7-isopropyl-1,1,4,4,6-pe...)
Affinity DataEC50:  9.89E+3nMAssay Description:Activation of PKC in human U1 cells infected with latent HIV-1 assessed as reversal of HIV-1 latency by measuring increase in p24 antigen level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed