BDBM50065458 CHEMBL3402761

SMILES O=c1ccc(nn1Cc1cccc(c1)-c1ncc(OCCN2CCOCC2)cn1)-c1cccc(c1)C#N

InChI Key InChIKey=QWPIOCUTERMEOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50065458   

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065458(CHEMBL3402761)
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065458(CHEMBL3402761)
Affinity DataIC50: 34nMAssay Description:Inhibition of c-Met kinase in human A549 cells assessed as inhibition of phosphorylation after 45 mins by electrochemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed