BDBM50065491 CHEMBL3402743

SMILES CN(C)CCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-c2cc(F)cc(F)c2)c1

InChI Key InChIKey=DZAVNSDHPJBMQG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50065491   

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065491(CHEMBL3402743)
Affinity DataIC50: 42nMAssay Description:Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065491(CHEMBL3402743)
Affinity DataIC50: 150nMAssay Description:Inhibition of c-Met kinase in human A549 cells assessed as inhibition of phosphorylation after 45 mins by electrochemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed