BDBM50066297 2-(2-Hydroxy-benzoyl)-5-methyl-4-[1-(4-nitro-phenyl)-meth-(E)-ylidene]-2,4-dihydro-pyrazol-3-one::CHEMBL110315

SMILES Cc1nn(C(=O)c2ccccc2O)c([O-])c1[CH+]c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=PKJCSNLNQWLWQX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066297   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066297(2-(2-Hydroxy-benzoyl)-5-methyl-4-[1-(4-nitro-pheny...)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066297(2-(2-Hydroxy-benzoyl)-5-methyl-4-[1-(4-nitro-pheny...)
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed