BDBM50066311 CHEMBL108773::N-[3-Chloro-2-(2-chloro-phenyl)-4-oxo-azetidin-1-yl]-2-hydroxy-benzamide

SMILES Oc1ccccc1C(=O)NN1C(C(Cl)C1=O)c1ccccc1Cl

InChI Key InChIKey=ZOODFJBHTYHNCK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50066311   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066311(N-[3-Chloro-2-(2-chloro-phenyl)-4-oxo-azetidin-1-y...)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibitory concentration as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066311(N-[3-Chloro-2-(2-chloro-phenyl)-4-oxo-azetidin-1-y...)
Affinity DataIC50: 2.41E+5nMAssay Description:Inhibitory concentration was evaluated as 50% inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integration in experiment IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066311(N-[3-Chloro-2-(2-chloro-phenyl)-4-oxo-azetidin-1-y...)
Affinity DataIC50: 2.48E+5nMAssay Description:Inhibitory concentration was evaluated as 50% inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integration in experiment IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed