BDBM50066326 4-[1-(3,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-2-(2-hydroxy-benzoyl)-5-methyl-2,4-dihydro-pyrazol-3-one::CHEMBL321391

SMILES C=c1[nH]n(C(=O)c2ccccc2O)c(=O)c1=Cc1ccc(OC)c(OC)c1

InChI Key InChIKey=UFOUTJZATODJGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066326   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066326BDBM50066326(4-[1-(3,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-2-(2...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066326BDBM50066326(4-[1-(3,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-2-(2...)
Affinity DataIC50: 500nMAssay Description:Inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed