BDBM50066661 8,10-Bis-(4-methoxy-benzenesulfonyl)-1,5-dithia-8,10-diaza-spiro[5.5]undecane-9-carboxylic acid hydroxyamide::CHEMBL118848

SMILES COc1ccc(cc1)S(=O)(=O)N1CC2(CN(C1C(=O)NO)S(=O)(=O)c1ccc(OC)cc1)SCCCS2

InChI Key InChIKey=XWGUPBCCRWJAMM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50066661   

TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066661(8,10-Bis-(4-methoxy-benzenesulfonyl)-1,5-dithia-8,...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066661(8,10-Bis-(4-methoxy-benzenesulfonyl)-1,5-dithia-8,...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066661(8,10-Bis-(4-methoxy-benzenesulfonyl)-1,5-dithia-8,...)
Affinity DataIC50: 79nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066661(8,10-Bis-(4-methoxy-benzenesulfonyl)-1,5-dithia-8,...)
Affinity DataIC50: 123nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed