BDBM50066713 CHEMBL3403145

SMILES Fc1ccc(cc1)-c1c(sc2nc(F)ccc12)S(=O)(=O)c1cc(F)cc(c1)C#N

InChI Key InChIKey=OLHINARPWOXBKB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066713   

TargetMetabotropic glutamate receptor 5(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066713(CHEMBL3403145)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066713(CHEMBL3403145)
Affinity DataIC50: 14nMAssay Description:Negative allosteric modulation of mGlu5 receptor in primary E17 rat embryo neuron assessed as ca2+ level by fluo-4/AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed