BDBM50067326 CHEMBL3237084

SMILES CCOC(=O)c1sc2ncnc(Nc3ccc(F)cc3)c2c1C

InChI Key InChIKey=DGZVFKBKGVKNKD-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50067326   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of South Australia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067326BDBM50067326(CHEMBL3237084)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of CDK9/cyclinT1 (unknown origin) using TAMRA-labeled eIF4E peptide as substrate incubated for 10 mins followed by addition of ATP measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
University of South Australia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067326BDBM50067326(CHEMBL3237084)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of CDK2/cyclinA (unknown origin) using TAMRA-labeled eIF4E peptide as substrate incubated for 10 mins followed by addition of ATP measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Institute of Molecular Biology and Genetics Nas of Ukraine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067326BDBM50067326(CHEMBL3237084)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of FGFR1 (unknown origin) using KKKSPGEYVNIEFG peptide substrate assessed as incorporation of [32P] into peptide by scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed