BDBM50068039 1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)-amino]-propyl}-3-[3-(1H-imidazol-4-yl)-propyl]-thiourea::CHEMBL103769
SMILES Clc1ccc(CN(CCCNC(=S)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
InChI Key InChIKey=UREJDUPKGMFJRU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50068039
Affinity DataKi: 6nMAssay Description:Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-4) subtypeMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:In vitro binding affinity at somatostatin receptor 4 in transfected BHK cells using [125 I]Tyr11-SRIF-14 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 621nMAssay Description:In vitro binding affinity at somatostatin 2 receptor in transfected HEK 293 cell using [125 I]Tyr11-SRIF-14 as radioligandMore data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Human)
National Center For Advancing Translation Sciences
Curated by ChEMBL
National Center For Advancing Translation Sciences
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of wild type glucocerebrosidase in human spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to subs...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Human)
National Center For Advancing Translation Sciences
Curated by ChEMBL
National Center For Advancing Translation Sciences
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair