BDBM50068259 CHEMBL3403369

SMILES CCn1c(NC(C)C)nc2c(csc2c1=O)C1CCN(C1)C(=O)C(C)C

InChI Key InChIKey=DKNQUIGACLDKSQ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068259   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL

LigandBDBM50068259(CHEMBL3403369)Copy SMILESCopy InChI

Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Kaken Pharmaceutical

Curated by ChEMBL

LigandBDBM50068259(CHEMBL3403369)Copy SMILESCopy InChI

Affinity DataIC50:  8.40nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI