BDBM50068287 CHEMBL3403346
SMILES CCn1c(NC(C)C)nc2c(csc2c1=O)C1CCN(C1)C(=O)c1cccc(C)n1
InChI Key InChIKey=OSIAQFSEAYCSKV-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50068287
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Kaken Pharmaceutical
Curated by ChEMBL
Kaken Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PDE3A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair