BDBM50068404 CHEMBL3403431

SMILES Nc1nc(N[C@@H]2C[C@H](CO)[C@@H](O)[C@H]2O)c(-c2nc3ccccc3s2)c(n1)C(F)(F)F

InChI Key InChIKey=IWJJUGZYXZFRJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50068404   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50068404(CHEMBL3403431)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed