BDBM50068898 BDBM50281588::CHEMBL147013::{1-[2-(1-Benzyl-3,3,3-trifluoro-2-oxo-propylcarbamoyl)-pyrrolidine-1-carbonyl]-2-methyl-propyl}-carbamic acid tert-butyl ester

SMILES CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)F

InChI Key InChIKey=RQBJCPKLQFRGBI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50068898   

TargetChymase(Human)
Green Cross Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50068898(CHEMBL147013 | {1-[2-(1-Benzyl-3,3,3-trifluoro-2-o...)
Affinity DataKi:  56nMAssay Description:Compound was evaluated for inhibitory activity against human heart chymase (HHC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Green Cross Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50068898(CHEMBL147013 | {1-[2-(1-Benzyl-3,3,3-trifluoro-2-o...)
Affinity DataKi:  113nMAssay Description:Compound was evaluated for inhibitory activity against ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin G(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068898(CHEMBL147013 | {1-[2-(1-Benzyl-3,3,3-trifluoro-2-o...)
Affinity DataKi:  1.70E+3nMAssay Description:The compound was tested for its potency to inhibit human Cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article