BDBM50070327 CHEMBL3408262

SMILES C[C@@H](Nc1cc(F)cc(F)c1)c1cc(cc2c1oc(cc2=O)N1CCOCC1)C(=O)N1CCC1

InChI Key InChIKey=NEJMTWJKPMUVTN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50070327   

LigandPNGBDBM50070327(CHEMBL3408262)
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3Kbeta in PTEN-null human MDA-MB-468 cells assessed as inhibition of Akt phosphorylation after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
LigandPNGBDBM50070327(CHEMBL3408262)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant PI3Kbeta using PIP2 by Kinase-Glo Plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
LigandPNGBDBM50070327(CHEMBL3408262)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant PI3Kdelta using PIP2 by Kinase-Glo Plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
LigandPNGBDBM50070327(CHEMBL3408262)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant PI3Kalpha using PIP2 by Kinase-Glo Plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
LigandPNGBDBM50070327(CHEMBL3408262)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant PI3Kgamma using PIP2 by Kinase-Glo Plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed