BDBM50071151 (2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine-2,4-dicarboxylic acid::CHEMBL304919

SMILES N[C@@]1(C[C@@H](N(CC(c2ccccc2)c2ccccc2)C1)C(O)=O)C(O)=O

InChI Key InChIKey=KWABXRJYGGENTG-YLJYHZDGSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50071151   

TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071151((2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071151((2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 4 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071151((2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 8 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071151((2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine...)
Affinity DataIC50:  6.36E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 3 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071151((2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine...)
Affinity DataIC50:  3.73E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50071151((2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed