BDBM50071364 5-Ethyl-5H-4,5,6-triaza-dibenzo[a,d]cycloheptene::CHEMBL308907

SMILES CCN1c2ncccc2C=Cc2cccnc12

InChI Key InChIKey=VUBCRLXMOBPPHX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50071364   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071364(5-Ethyl-5H-4,5,6-triaza-dibenzo[a,d]cycloheptene |...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for inhibitory activity against HIV-1 wild type reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071364(5-Ethyl-5H-4,5,6-triaza-dibenzo[a,d]cycloheptene |...)
Affinity DataIC50: 40nMAssay Description:Compound was tested for inhibitory activity against HIV-1 wild type reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071364(5-Ethyl-5H-4,5,6-triaza-dibenzo[a,d]cycloheptene |...)
Affinity DataIC50: 230nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (L1001)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071364(5-Ethyl-5H-4,5,6-triaza-dibenzo[a,d]cycloheptene |...)
Affinity DataIC50: 1.50E+3nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (K103N)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071364(5-Ethyl-5H-4,5,6-triaza-dibenzo[a,d]cycloheptene |...)
Affinity DataIC50: 2.50E+3nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (Y181C)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed