BDBM50072160 2,5-Bis-(naphthalen-2-ylsulfanyl)-1H-pyrrole-3,4-dicarbonitrile::CHEMBL330195

SMILES N#Cc1c(Sc2ccc3ccccc3c2)[nH]c(Sc2ccc3ccccc3c2)c1C#N

InChI Key InChIKey=RKZVAHQAAAMDRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072160   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072160(2,5-Bis-(naphthalen-2-ylsulfanyl)-1H-pyrrole-3,4-d...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of the dual specificity kinase MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072160(2,5-Bis-(naphthalen-2-ylsulfanyl)-1H-pyrrole-3,4-d...)
Affinity DataIC50: 2.89E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed