BDBM50072242 4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric acid::CHEMBL99339

SMILES OC(CC(=O)c1ccc(Cl)c(Cl)c1)C(O)=O

InChI Key InChIKey=OFKDXERWJCPSAE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072242   

TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072242(4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50: 300nMAssay Description:Compound was evaluated for inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072242(4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50: 1.40E+3nMAssay Description:Compound was evaluated for inhibition of rat liver KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072242(4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50: 3.30E+3nMAssay Description:Compound was evaluated for inhibition of human recombinant KYN 3-OHaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed