BDBM50072616 CHEMBL3410025

SMILES CC(C)NC(=O)c1cccc(NC(=O)Nc2ccc(cc2)-c2ncnc3[nH]c(C)c(C)c23)c1

InChI Key InChIKey=JYIXNUGPDHTKQF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072616   

TargetLIM domain kinase 1(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072616(CHEMBL3410025)
Affinity DataIC50: 80nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072616(CHEMBL3410025)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ROCK2 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK peptide substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072616(CHEMBL3410025)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human ROCK1 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK peptide substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed