BDBM50072829 CHEMBL3410039

SMILES Cc1c[nH]c2ncnc(-c3ccc(NC(=O)N(CCO)c4ccc(F)cc4)cc3)c12

InChI Key InChIKey=FCMRBYJIHLJQSI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50072829   

TargetLIM domain kinase 1(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072829(CHEMBL3410039)
Affinity DataIC50: 86nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072829(CHEMBL3410039)
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of human ROCK2 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK peptide substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072829(CHEMBL3410039)
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of human ROCK1 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK peptide substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072829(CHEMBL3410039)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human JNK3 using ATF2 substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed