BDBM50074204 3-{3-[4-(1H-Imidazol-2-ylmethyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole::CHEMBL164413

SMILES C(CN1CCN(Cc2ncc[nH]2)CC1)Cc1c[nH]c2ccc(cc12)-n1cnnc1

InChI Key InChIKey=VIRXHPTUPCUXTR-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074204   

Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074204(3-{3-[4-(1H-Imidazol-2-ylmethyl)-piperazin-1-yl]-p...)
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]5-HT binding to the cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074204(3-{3-[4-(1H-Imidazol-2-ylmethyl)-piperazin-1-yl]-p...)
Affinity DataEC50:  2nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding in CHO cells expressing the human 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074204(3-{3-[4-(1H-Imidazol-2-ylmethyl)-piperazin-1-yl]-p...)
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed