BDBM50075751 4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrol-2-yl]-benzonitrile::CHEMBL158989
SMILES Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)-c1ccc(cc1)C#N
InChI Key InChIKey=NVWTWHYQHRAFNN-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50075751
Affinity DataIC50: 230nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human glucagon receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against p38-alpha kinaseMore data for this Ligand-Target Pair