BDBM50075788 4-[5-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrrol-2-yl]-pyridine::CHEMBL160281

SMILES Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)-c1cccc(Cl)c1

InChI Key InChIKey=YOFQALFMYOUGSF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50075788   

TargetGlucagon receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075788(4-[5-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...)
Affinity DataIC50:  460nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075788(4-[5-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...)
Affinity DataIC50:  990nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075788(4-[5-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...)
Affinity DataIC50:  421nMAssay Description:Antagonist activity at human glucagon receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075788(4-[5-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...)
Affinity DataIC50:  40nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075788(4-[5-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...)
Affinity DataIC50:  420nMAssay Description:Inhibitory activity against p38-alpha kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed