BDBM50076191 CHEMBL3416022

SMILES N[C@H]1CCCC[C@H]1Nc1ccc(C(N)=O)c(Nc2cccc3cc[nH]c23)n1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076191   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50076191(CHEMBL3416022)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated Qpatch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50076191(CHEMBL3416022)
Affinity DataIC50:  165nMAssay Description:Inhibition of Syk (unknown origin) using 5-Fluo-Ahx-GAPDYENLQELNKK-Amide as substrate after 60 mins by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50076191(CHEMBL3416022)
Affinity DataIC50:  438nMAssay Description:Inhibition of Syk in anti-igM stimulated human Ramos B cells assessed as phospho-BLNK level preincubated for 30 mins followed by anti-IgM stimulation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed