BDBM50076192 CHEMBL3416021

SMILES N[C@H]1CCCC[C@H]1Nc1ccc(C(N)=O)c(Nc2cccc(c2)-n2nccn2)n1

InChI Key InChIKey=CAPOVEGNVPHPNW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076192   

TargetTyrosine-protein kinase SYK(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50076192(CHEMBL3416021)
Affinity DataIC50: 19nMAssay Description:Inhibition of Syk (unknown origin) using 5-Fluo-Ahx-GAPDYENLQELNKK-Amide as substrate after 60 mins by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50076192(CHEMBL3416021)
Affinity DataIC50: 445nMAssay Description:Inhibition of Syk in anti-igM stimulated human Ramos B cells assessed as phospho-BLNK level preincubated for 30 mins followed by anti-IgM stimulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50076192(CHEMBL3416021)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by automated Qpatch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed