BDBM50076501 19-methoxy-24-methyl-4,24-diazahexacyclo[12.7.3.01,13.03,11.05,10.016,21]tetracosa-3(11),5(10),6,8,16,18,20-heptaene-13,20-diol::CHEMBL416647

SMILES COc1ccc2C[C@H]3N(C)CC[C@@]4(Cc5[nH]c6ccccc6c5C[C@@]34O)c2c1O

InChI Key InChIKey=NVKFKYFEFLFZKJ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50076501   

TargetDelta-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50076501(19-methoxy-24-methyl-4,24-diazahexacyclo[12.7.3.01...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076501(19-methoxy-24-methyl-4,24-diazahexacyclo[12.7.3.01...)
Affinity DataKi:  218nMAssay Description:Binding affinity towards Opioid receptor delta 1 by the displacement of [3H]DADLE radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50076501(19-methoxy-24-methyl-4,24-diazahexacyclo[12.7.3.01...)
Affinity DataKi:  1.85E+3nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076501(19-methoxy-24-methyl-4,24-diazahexacyclo[12.7.3.01...)
Affinity DataKi:  2.85E+3nMAssay Description:Binding affinity towards Opioid receptor mu 1 by the displacement of [3H]DAMGO radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50076501(19-methoxy-24-methyl-4,24-diazahexacyclo[12.7.3.01...)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]U50488 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076501(19-methoxy-24-methyl-4,24-diazahexacyclo[12.7.3.01...)
Affinity DataKi: >6.70E+3nMAssay Description:Ability to displace [3H]U-69593 radioligand from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed