BDBM50076575 3-{5-[4-amino(imino)methylaminobutyl]-4,5-dihydro-3-isoxazolylcarboxamido}-2-mesitylsulfonamido-(2S)-propanoic acid::3-{[5-(4-Guanidino-butyl)-4,5-dihydro-isoxazole-3-carbonyl]-amino}-2-(2,4,6-trimethyl-benzenesulfonylamino)-propionic acid::CHEMBL265074

SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNC(N)=N)C1)C(O)=O

InChI Key InChIKey=ONXOUPOQMPFEEV-LWKPJOBUSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50076575   

TargetIntegrin alpha-V/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076575(3-{5-[4-amino(imino)methylaminobutyl]-4,5-dihydro-...)
Affinity DataIC50:  169nMAssay Description:Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076575(3-{5-[4-amino(imino)methylaminobutyl]-4,5-dihydro-...)
Affinity DataIC50:  340nMAssay Description:Antagonistic activity against fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076575(3-{5-[4-amino(imino)methylaminobutyl]-4,5-dihydro-...)
Affinity DataIC50:  0.700nMAssay Description:Antagonistic activity against vitronectin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076575(3-{5-[4-amino(imino)methylaminobutyl]-4,5-dihydro-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of platelet aggregation in human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed