BDBM50076872 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-trifluoromethyl-thiazole::CHEMBL265585

SMILES CS(=O)(=O)c1ccc(cc1)-c1sc(nc1-c1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=SAVMISCIBLZUAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076872   

TargetProstaglandin G/H synthase 2(Human)
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076872(4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human cyclooxygenase-2 (hCOX-2) enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076872(4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human cyclooxygenase-1 (hCOX-1) enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed