BDBM50077684 CHEMBL283237::Nicotinic acid 2-{4-[(3R,4R)-3-(naphthalen-2-ylmethoxy)-piperidin-4-yl]-phenoxy}-ethyl ester

SMILES O=C(OCCOc1ccc(cc1)[C@H]1CCNC[C@@H]1OCc1ccc2ccccc2c1)c1cccnc1

InChI Key InChIKey=GTSLCYHNKKYWIT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077684   

TargetRenin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077684(Nicotinic acid 2-{4-[(3R,4R)-3-(naphthalen-2-ylmet...)
Affinity DataIC50: 580nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed