BDBM50077825 3-(2-Fluoro-3-{4-[2-(3-fluoro-phenyl)-propyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole::CHEMBL65321

SMILES CC(CN1CCN(CC(F)Cc2c[nH]c3ccc(cc23)-n2cnnc2)CC1)c1cccc(F)c1

InChI Key InChIKey=OSMWOUQXOWZMEO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077825   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077825(3-(2-Fluoro-3-{4-[2-(3-fluoro-phenyl)-propyl]-pipe...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of specific [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077825(3-(2-Fluoro-3-{4-[2-(3-fluoro-phenyl)-propyl]-pipe...)
Affinity DataEC50:  1.90nMAssay Description:Agonist-induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077825(3-(2-Fluoro-3-{4-[2-(3-fluoro-phenyl)-propyl]-pipe...)
Affinity DataIC50:  280nMAssay Description:Displacement of specific [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed