BDBM50078 2-thiophenecarboxylic acid [3-[(Z)-[1-(3-chloro-4-fluorophenyl)-3,5-dioxo-4-pyrazolidinylidene]methyl]phenyl] ester::3-{[1-(3-chloro-4-fluorophenyl)-3,5-dioxo-4-pyrazolidinylidene]methyl}phenyl 2-thiophenecarboxylate::CHEMBL1504817::MLS000534145::SMR000141582::[3-[(Z)-[1-(3-chloranyl-4-fluoranyl-phenyl)-3,5-bis(oxidanylidene)pyrazolidin-4-ylidene]methyl]phenyl] thiophene-2-carboxylate::[3-[(Z)-[1-(3-chloro-4-fluorophenyl)-3,5-dioxopyrazolidin-4-ylidene]methyl]phenyl] thiophene-2-carboxylate::cid_1007600::thiophene-2-carboxylic acid [3-[(Z)-[1-(3-chloro-4-fluoro-phenyl)-3,5-diketo-pyrazolidin-4-ylidene]methyl]phenyl] ester

SMILES Fc1ccc(cc1Cl)N1NC(=O)\C(=C\c2cccc(OC(=O)c3cccs3)c2)C1=O

InChI Key InChIKey=JNUIQGKVFFMDLX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078   

TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50078(2-thiophenecarboxylic acid [3-[(Z)-[1-(3-chloro-4-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of EGFR after 50 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50078(2-thiophenecarboxylic acid [3-[(Z)-[1-(3-chloro-4-...)
Affinity DataIC50: 7.17E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay