BDBM50078133 (S)-2-Amino-4-methyl-pentane-1-thiol::2-Amino-4-methyl-pentane-1-thiol::CHEMBL448735

SMILES CC(C)C[C@H](N)CS

InChI Key InChIKey=GXEDNWSUKCJLLB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50078133   

TargetAminopeptidase N(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50078133(2-Amino-4-methyl-pentane-1-thiol | (S)-2-Amino-4-m...)
Affinity DataIC50: 8nMAssay Description:Inhibition of FLAG-tagged human recombinant Aminopeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAminopeptidase N(Pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50078133(2-Amino-4-methyl-pentane-1-thiol | (S)-2-Amino-4-m...)
Affinity DataKi:  22nMAssay Description:Inhibition of pig kidney Aminopeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50078133(2-Amino-4-methyl-pentane-1-thiol | (S)-2-Amino-4-m...)
Affinity DataIC50: 110nMAssay Description:Inhibition of C-terminal Hexa-histidine-tagged human recombinant ERAP1 expressed in Sf9 cells using L-AMC as substrate incubated for 15 mins by Micha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50078133(2-Amino-4-methyl-pentane-1-thiol | (S)-2-Amino-4-m...)
Affinity DataIC50: 610nMAssay Description:Inhibition of C-terminal Hexa-histidine-tagged human recombinant ERAP2 expressed in Sf9 cells using R-AMC as substrate incubated for 15 mins by Micha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed