BDBM50078607 CHEMBL3415153
SMILES Fc1cc(cc2CCc3nncn3-c12)-c1cccnc1
InChI Key InChIKey=ADUZVRQZQAEEME-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50078607
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 172nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [14C]-deoxycorticosterone substrate incubated for 6 hrs by HPTLC methodMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [14C]-deoxycorticosterone substrate incubated for 6 hrs by HPTLC methodMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of CYP11B1 (unknown origin)More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing human CYP17 and NADPH-P450 reductaseMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 172nMAssay Description:Inhibition of CYP11B2 (unknown origin)More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsomes using [1beta-3H]androstenedione substrateMore data for this Ligand-Target Pair