BDBM50078682 CHEMBL3415618

SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=YZMMIKVAAIZQTM-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50078682   

TargetHistone deacetylase 8(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078682(CHEMBL3415618)
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078682(CHEMBL3415618)
Affinity DataIC50: 250nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078682(CHEMBL3415618)
Affinity DataEC50:  1.62E+4nMAssay Description:Inhibition of HDAC6 in human A549 cells assessed as induction of tubulin acetylation after 17 to 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50078682(CHEMBL3415618)
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed