BDBM50079033 5-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-[1,3,4]thiadiazole-2-sulfonic acid amide::CHEMBL88232

SMILES NS(=O)(=O)c1nnc(s1)N1C(=O)c2cccnc2C1=O

InChI Key InChIKey=ABZUQTACHNXKQR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079033   

TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50079033(5-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-y...)
Affinity DataKi:  8nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II (hCA II, cytosolic form).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50079033(5-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-y...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity against bovine lung microsomes carbonic anhydrase isozyme IV (bCA IV).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50079033(5-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-y...)
Affinity DataKi:  39nMAssay Description:Inhibition of human cloned Carbonic anhydrase I (hCA I,cytosolic form)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2012
Entry Details Article
PubMed