BDBM50079175 1-[1-(3-Chloro-benzyl)-piperidin-4-yl]-5-methyl-4-phenyl-1,3-dihydro-imidazol-2-one::CHEMBL93832

SMILES Cc1c([nH]c(=O)n1C1CCN(Cc2cccc(Cl)c2)CC1)-c1ccccc1

InChI Key InChIKey=PDJMURIRAHUSPJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079175   

TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079175(1-[1-(3-Chloro-benzyl)-piperidin-4-yl]-5-methyl-4-...)
Affinity DataKi:  0.460nMAssay Description:Affinity to displace [3H]spiperone from cloned human Dopamine receptor D4 stably expressed in HEK393 cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079175(1-[1-(3-Chloro-benzyl)-piperidin-4-yl]-5-methyl-4-...)
Affinity DataKi:  1.30E+3nMAssay Description:Affinity to displace [3H]spiperone from cloned human Dopamine receptor D2 stably expressed in CHO cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079175(1-[1-(3-Chloro-benzyl)-piperidin-4-yl]-5-methyl-4-...)
Affinity DataKi: >4.70E+3nMAssay Description:Affinity to displace [3H]spiperone from cloned human Dopamine receptor D3 (hD3) stably expressed in HEK393 cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed